Fundamentals of Genetic Epidemiology PDF
By:Muin J. Khoury,Terri H. Beaty,Bernice H. Cohen
Published on 1993 by Oxford University Press, USA
With continued progress in mapping and sequencing of the human genome, and increasing recognition of the role of genes in disease etiology, there is a need for a more sophisticated approach to the investigation of the causes of complex chronic diseases. This text integrates the principles, methods and approaches of epidemiology and genetics in the study of disease etiology. After a brief historical overview of genetics and epidemiology and their gradual rapprochement, the authors define the central theme of genetic epidemiology as the study of the role of genetic factors and their interaction with environmental factors in the occurrence of disease in populations. They describe fundamental research strategies of genetic epidemiology including population and family studies. Among the former are the study of the distribution of genetic traits and the role of nonspecific genetic indicators (such as inbreeding and admixture) in the occurrence of diseases. Among the latter are the analysis of familial aggregation of disease and its causes by epidemiologic methods as well as techniques of formal genetic analysis (variance components, segregation and linkage analysis). Finally, the authors discuss the increasing applications of genetic epidemiology in preventive medicine, public health surveillance, and the emerging ethical issues regarding use of genetic information in society.
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Book ID of Fundamentals of Genetic Epidemiology's Books is VC7BAgAAQBAJ, Book which was written byMuin J. Khoury,Terri H. Beaty,Bernice H. Cohenhave ETAG "yMqNvEfBjt4"
Book which was published by Oxford University Press, USA since 1993 have ISBNs, ISBN 13 Code is 9780195052886 and ISBN 10 Code is 0195052889
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